Collects Ultimate Six (2003) #1-7 and Ultimate Spider-Man (2000-2009 1st Series) #46 and #54-59.
Cover by John Cassaday. The Green Goblin. Dr. Octopus. Electro. Kraven the Hunter. Sandman. Five of Spider-Man's deadliest foes have banded together as an unstoppable force of evil! Will Spider-Man and the Ultimates be enough to stop these criminal masterminds before their reign of terror spreads across the world? And who will they target as the sixth member of their deadly alliance? Then, a movie studio is making a summer blockbuster about Spider-Man, and the Ultimate wall-crawler swings by the set to give the producers a piece of his mind. But someone else is even hotter about being in the film than Spidey: Dr. Octopus, who may just shut down the production if he doesn't get final edit! As the cameras roll, Spider-Man and Doc Ock go head-to-head behind the scenes!