The Avengers Vol. 1 (1963-1996) #315

Plot

The universe has vanished! Except for two small pockets of life! One pocket is the Avengers control room with five souls inside! And the other is the Polydyne Industries laboratory with Nebula, Professor Harker, and a few assistants clinging to life! The professor's powerful universal compressor has run amok and now threatens to annihilate everything! Thor uses his mighty mjolnir to bring the Avengers into the Polydyne lab! And then and there, the star-spangled avenger, the Prince of Asgard, the enchanting Eternal, and your friendly neighborhood Spider-Man fight to save the cosmos from total annihilation! (mycomicshop.com)