They crossed the streams! Turtles and scientists, working together... and they're back for more! The two popculture phenomenons join forces again in this sequel to the smash hit to fight a threat more extreme than anything either of them have ever faced.
An enemy from Master Splinter's past is back and hungry for revenge. To get it, he'll summon the most dangerous foe that the Turtles have ever encountered the Collectors, shapeshifting demons that can pass through dimensions at will and cannot be stopped once they have been summoned to harvest a soul. To save themselves from the clutches of the Collectors, the Turtles team up with the Ghostbusters, the only people who have ever faced them and lived to tell the tale, in a battle that turns into a chase across dimensions both incredible and terrifying.